Symptomatic polycystic liver disease: a rare indication of hepatectomy.

We present the case of forty-four-year-old woman with autosomal dominant Polycystic liver disease (PLD) without kidney disease diagnosed for 18 years ago. She experienced progressive abdominal distension and malnutrition over the previous twelve months. The patient had no other comorbidities. Physical examination revealed an 8 cm hepatomegaly in the right hypochondrium region. Liver function analysis was normal. CT scan showed multiple liver cysts with smooth and regular walls, predominantly in the right lobe which was considered as type III according to Gigot´s classification. Due to the significant hepatomegaly, conventional surgery was performed. Exploration showed multiple cysts of varying sizes on the liver surface, with diffuse involvement of the right hemiliver. Standard right lobe mobilization was technically not possible. Fenestration was performed in dominant superficial cysts, to allow access to the deeper cysts and liver parenchyma. A right hepatectomy was carried up using ultrasound devices and ultrasonic aspirator. And the biggest cysts located in the surface of left hepatic lobe were surgically unroofed. No surgical complications occurred, and the patient was discharged 5 days after the intervention.

Hepatectomía asociada a resección venosa portal en colangiocarcinoma perihiliar / Hepatectomy associated with protal vein resection in perihilar cholangiocarcinoma

RESUMEN El colangiocarcinoma es una neoplasia infrecuente que, debido a su localización anatómica, plantea una dificultad técnica para su resolución quirúrgica. La cirugía en el colangiocarcinoma perihiliar sigue siendo el único tratamiento curativo con el que se consiguen las mejores tasas de supervivencia a los 5 años. La invasión de la vena porta conlleva la necesidad de asociar una resección portal y su correspondiente reconstrucción. Sin embargo, la invasión tumoral de la vena porta es, en la mayoría de los casos, un hallazgo intraoperatorio, por lo que es importante contar con opciones para eventuales reconstrucciones vasculares. A continuación presentamos un caso de resolución quirúrgica de colangiocarcinoma perihiliar con identificación intraoperatoria de compromiso portal.

ABSTRACT Cholangiocarcinoma is a rare neoplasm and a difficult challenge for the surgeon because of its anatomic location. Surgery remains the only curative option for perihilar cholangiocarcinoma with the best survival rates at 5 years. Portal vein invasion requires portal vein resection and its corresponding reconstruction. However, as portal vein invasion is an intraoperative finding in most cases it is important to count with options for in case vascular reconstructions are needed. We report a case of perihilar cholangiocarcinoma successfully treated with surgery with portal vein invasion identified intraoperatively.

Evaluación de los resultados del trasplante hepático con hígados que nadie quiere / Result evaluation of liver transplantation with livers that nobody wants

INTRODUCCIÓN: La escasez de donantes para suplir la demanda de trasplantes es un problema Mundial. "Hígados que nadie quiere" (HNQ) define injertos que fueron rechazados numerosas veces por varios centros antes de su aceptación. OBJETIVO: evaluar los resultados en la utilización de "HNQ" en nuestro centro. Fuente de datos CRESI-SINTRA y una base prospectiva, Periodo 2013-2016. MÉTODOS: Estudio retrospectivo, dos grupos pre-determinados: 1. Pacientes que recibieron un órgano más allá del percentilo 75 de mediana de rechazos 2. Resto de los receptores. RESULTADOS: Se realizaron 1325 trasplantes a nivel nacional, con una mediana de rechazos previos al implante de 5 (IQR3-11). 153 fueron realizados en el HEC y la mediana de rechazos fue de 7 (IQR3-18); 55/36% de esos injertos mas allá de p75, ninguno fue usado para falla fulminante. Comparando 1 vs 2 (55 vs 72), no hubo diferencias estadísticamente significativas en la edad (51 años IQR45-60 vs 50 años IQR39-59 p=0.53), incidencia de falla primaria del injerto (RR 0.65 IC95%0.33-1.32 p=0.19), extubacion temprana (RR 1.16 IC95%0.43-3.16p=0.78),o diálisis (RR 1.36 IC95%0.84-2.21 p=0.26); tampoco en la duración de estadía en UTI (4 días IQR3-6 vs 5 días IQR 3-9 p=0.12) u hospitalaria (8 días IQR 6-14 vs 1.5 días IQR 8-17.5 p=0.06), sobrevida del injerto (p=0.51) y del paciente (p=0.59). El MELD del receptor fue la única diferencia (24 IQR22-25 vs 28 IQR25-33 p<0.05: Un tercio de la población de nuestro centro recibió "HNQ" (injertos rechazados previamente 12 veces), con similares resultados. Futuras investigaciones deberían determinar la causa de esos rechazos.

INTRODUCTION: Donor scarcity to supply the demand for transplants is a global problem. "Livers that nobody wants" (LNW) are those grafts that were refused by several centers multiple times before being accepted. OBJECTIVE: to evaluate the results in the use of "LNW" in our center. Data source: CRESI-SINTRA and a prospective database, period 2013-2016. METHODS: Retrospective study in two predetermined groups: 1. Patients who received an organ beyond the 75th percentile of median rejections 2. The rest of recipients. RESULTS: At national level, 1325 transplantations were made, its median refusals prior to implantation being 5 (IQR3-11), of which 153 were made in the HEC and the median refusals were 7 (IQR3-18); out of 55/36% of these grafts beyond the 75th p, none were used in fulminant hepatic failure. In comparing 1 vs 2 groups (55 vs 72), there were no statistically significant differences in age (51 years IQR45-60 vs 50 years IQR39-59 p=0.53), incidence ofdraft primary failure (RR 0.65 IC95%0.33-1.32 p=0.19), early extubation (RR 1.16 IC95%0.43- 3.16p=0.78),or dialysis requirement (RR 1.36 IC95%0.84-2.21 p=0.26); there were no differences either in the ICU stay (4 days IQR3-6 vs 5 days IQR 3-9 p=0.12) or in hospital stay(8 days IQR 6-14 vs 1.5 days IQR 8-17.5 p=0.06), draft survival (p=0.51) and patient survival (p=0.59). The only difference was in the MELD score of the receptor (24 IQR22-25 vs 28 IQR25-33 p<0.05:). A third of the population in our center received LNW (drafts previously refused 12 times) and showed similar results. The cause of these refusals should be determined by future research.

[Surgical resection with curative intent of hilar cholangiocarcinoma. Our experience]. / Resección quirúrgica con intención curativa del colangiocarcinoma hiliar. Nuestra experiencia.

INTRODUCTION: Surgery is the treatment of choice for hilar cholangiocarcinoma (HCC). Obtaining tumor-free margins (RO resection) has been reported as the only prognostic factor associated with increased survival. The aim of this study was to analyze a consecutive series of patients operated with curative intent over a 14-year period. MATERIAL AND METHODS: This is a retrospective study of patients operated with curative intent between 1994 and 2008. Hepatic resection was associated with resection of segment 1, extrahepatic bile duct and lymph node dissection in all cases. RESULTS: 40 patients, 62% male with a mean age of 58.2 years. Jaundice was the most common presenting symptom (70%). Biliary confluence was compromised in 62% oftumors. Thirty-nine patients underwent major hepatectomy with 95% RO resections and 6 associated vascular resections. Postoperative morbidity was 37.5% and mortality 10%. Overall survival and disease-free survival at 1, 3 and 5 years was 88% and 63%, 55% and 34%, and 43% and 24%, respectively. CONCLUSION: The association of major hepatectomy with caudate lobe resection and vascular resection when needed, was associated with 95% tumor-free margin and morbidity and mortality rate according to the standards of the international literature. While it is necessary a greater number of cases, associated vascular resection seems to be a feasible and safe option in the treatment of locally advanced HCC.

La relaparoscopía en las complicaciones postoperatorias de la colecistectomia / Laparoscopy in postoperative complications of cholecystectomy

Objetivo: Evaluar la utilidad de la relaparoscopía para el diagnóstico y tratamiento de complicaciones post colecistectomía. Lugar: Hospital de alta complejidad. Población: 2755 colecistectomías laparoscópicas, con 14 (0.5%) relaparoscopias entre agosto 2004 - diciembre 2010. Método: Análisis retrospectivo de base de datos. Resultados: 14 relaparoscopías; 6 por complicaciones hemorrágicas, 6 biliares y 2 perforaciones intestinales. Conclusión: La relaparoscopía fue efectiva para el diagnóstico y tratamiento de complicaciones post colecistectomía. La principal indicación fue el dolor siendo el diagnóstico por imágenes poco específico.